Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893418 | 0.93 | OPRM1 (0.36) | CA2CA1DNM1TSHR | |
| SCHEMBL18893422 | 0.90 | TAS1R3 (0.30) | — | |
| SCHEMBL25888208 | 0.86 | ZDHHC7 (0.39) | CA2DNM1TSHR | |
| SCHEMBL18893510 | 0.86 | CA2 (0.42) | CA2CA1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL24191894 | 0.85 | ALDH1A1 (0.40) | CA2CA1ALDH1A1TSHRMAPK1 | |
| SCHEMBL25907446 | 0.85 | CA1 (0.34) | CA2CA1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL25907447 | 0.85 | CA1 (0.34) | CA2CA1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL25907449 | 0.85 | CA1 (0.34) | CA2CA1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL14266734 | 0.82 | ALDH1A1 (0.41) | CA2CA1ALDH1A1MAPK1PLA2G2C | |
| SCHEMBL25522121 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | CA2 3229/4885CA1 4205/4885ALDH1A1 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.