Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17806325 | 0.89 | KDM4E (0.49) | SRD5A1SRD5A2TP53PDK1PDK2 | |
| SCHEMBL20173807 | 0.85 | SRD5A1 (0.56) | SRD5A1SRD5A2TP53KDM4ENPC1 | |
| SCHEMBL25873261 | 0.84 | TP53 (0.46) | TP53NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL20173808 | 0.84 | RARA (0.47) | TP53PDK1PDK2PDK3PDK4 | |
| SCHEMBL23054219 | 0.83 | MEN1 (0.45) | TP53KDM4ENPC1SMN1; SMN2RAB9A | |
| SCHEMBL21792031 | 0.81 | KDM4E (0.56) | SRD5A1SRD5A2TP53PDK1PDK2 | |
| SCHEMBL12900265 | 0.79 | SRD5A1 (0.54) | SRD5A1SRD5A2TP53PDK1PDK2 | |
| SCHEMBL21776847 | 0.78 | NOTUM (0.65) | SRD5A1SRD5A2TP53PDK1PDK2 | |
| SCHEMBL5682339 | 0.78 | SRD5A1 (0.56) | SRD5A1SRD5A2TP53PDK1PDK2 | |
| SCHEMBL20173809 | 0.78 | SRD5A1 (0.54) | SRD5A1SRD5A2TP53KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
| WO-2020043866-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | GOT2, GOT1, OAT | SRD5A1 736/4885SRD5A2 939/4885TP53 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.