Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795648 | 0.85 | XDH (0.39) | FFAR4DGAT1GRM4 | |
| SCHEMBL21795636 | 0.85 | XDH (0.39) | FFAR4DGAT1GRM4 | |
| SCHEMBL21795670 | 0.82 | KCNH2 (0.35) | FFAR4DGAT1GRM4 | |
| SCHEMBL15420619 | 0.82 | FFAR4 (0.41) | FFAR4DGAT1GRM4 | |
| SCHEMBL12987351 | 0.78 | GRIA2 (0.38) | FFAR4MAPK1 | |
| SCHEMBL12988024 | 0.78 | GRIA2 (0.38) | FFAR4MAPK1 | |
| SCHEMBL12988368 | 0.78 | GRIA2 (0.38) | FFAR4MAPK1 | |
| SCHEMBL15420690 | 0.78 | GRIA2 (0.38) | FFAR4MAPK1 | |
| SCHEMBL15420449 | 0.78 | GRIA2 (0.38) | FFAR4MAPK1 | |
| SCHEMBL21795663 | 0.78 | XDH (0.39) | FFAR4DGAT1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |