Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ATF4 | P18848 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795636 | 1.00 | XDH (0.39) | XDHGPR119ATF4FFAR4GRM4 | |
| SCHEMBL21795663 | 0.88 | XDH (0.39) | XDHGPR119FFAR4GRM4DGAT1 | |
| SCHEMBL21795659 | 0.88 | NPC1 (0.39) | XDHGPR119ATF4FFAR4 | |
| SCHEMBL21795638 | 0.87 | KDM4E (0.42) | XDHGPR119KDM1A | |
| SCHEMBL21795667 | 0.85 | FFAR4 (0.37) | FFAR4GRM4DGAT1 | |
| SCHEMBL21795670 | 0.85 | KCNH2 (0.35) | GPR119FFAR4GRM4DGAT1 | |
| SCHEMBL15420648 | 0.80 | DGAT1 (0.39) | XDHATF4FFAR4GRM4DGAT1 | |
| SCHEMBL12989748 | 0.80 | DGAT1 (0.39) | XDHATF4FFAR4GRM4DGAT1 | |
| SCHEMBL12989747 | 0.80 | DGAT1 (0.39) | XDHATF4FFAR4GRM4DGAT1 | |
| Hydrochloric Acid SCHEMBL15420859 | 0.79 | KDM1A (0.41) | XDHATF4FFAR4GRM4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |