Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12986558 | 0.91 | GRM5 (0.38) | PARP10PARP15FFAR4DGAT1FFAR1 | |
| SCHEMBL21795636 | 0.85 | XDH (0.39) | GPR119FFAR4DGAT1GRM4 | |
| SCHEMBL21795648 | 0.85 | XDH (0.39) | GPR119FFAR4DGAT1GRM4 | |
| SCHEMBL21795667 | 0.82 | FFAR4 (0.37) | FFAR4DGAT1GRM4 | |
| SCHEMBL15420401 | 0.82 | KCNH2 (0.38) | KCNH2GPR119FFAR4DGAT1FFAR1 | |
| SCHEMBL15420745 | 0.78 | SMO (0.40) | KCNH2GPR119DGAT1FFAR1CYP2C8 | |
| SCHEMBL15420466 | 0.78 | SMO (0.40) | KCNH2GPR119DGAT1FFAR1CYP2C8 | |
| SCHEMBL12987399 | 0.78 | SMO (0.40) | KCNH2GPR119DGAT1FFAR1CYP2C8 | |
| SCHEMBL21795663 | 0.78 | XDH (0.39) | GPR119FFAR4DGAT1GRM4 | |
| SCHEMBL15419974 | 0.78 | SMO (0.34) | KCNH2GPR119DGAT1FFAR1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |