SCHEMBL2179698

SCHEMBL2179698

O=C(CI)Nc1ccc(C(=O)ON2C(=O)CC(S(=O)(=O)O)C2=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
HPGD P15428 3/20 0.40
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
MAPT P10636 6/20 0.37
GAA P10253 1/20 0.37
MPI P34949 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPK1 P28482 2/20 0.37
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382448 0.89 ALDH1A1 (0.38) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL16848723 0.89 KMT2A (0.42) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL10105974 0.88 L3MBTL1 (0.42) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL2633144 0.83 ALDH1A1 (0.44) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL13221517 0.83 ALDH1A1 (0.42) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL6254346 0.80 ALDH1A1 (0.33) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL21504417 0.80 HPGD (0.40) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL4432965 0.80 GAA (0.36) ALDH1A1HPGDMEN1KMT2AGAA
SCHEMBL21167217 0.79 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL109045 0.79 ALDH1A1 (0.54) ALDH1A1HPGDMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2038 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144860-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2026-05-28 US claimed
US-12458691-B2 HIV-1 ENV fusion peptide immunogens and their use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-11-04 US claimed
US-20250295745-A1 CROSS-LINKED TUMOR LYSATE SPHERICAL NUCLEIC ACIDS AS CANCER VACCINES NORTHWESTERN UNIVERSITY 2025-09-25 US claimed
US-12329822-B2 Antimicrobial tailored chitosan UNIVERSITÉ DE GENVE (CH) 2025-06-17 US claimed
CN-112533640-B Targeting of M2-type tumor-associated macrophages using melittin-based apoptosis-inducing peptides 双亥生命科学株式会社 2025-02-28 CN claimed
US-20240293524-A1 MULTIPLE FUNCTIONALIZED noMV CONJUGATES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-09-05 US claimed
EP-3965887-B1 ANTIMICROBIAL CHITOSAN UNIV GENEVE (CH) 2024-02-28 EP claimed
US-20240052005-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2024-02-15 US claimed
WO-2023220678-A1 CROSS-LINKED TUMOR LYSATE SPHERICAL NUCLEIC ACIDS AS CANCER VACCINES NORTHWESTERN UNIVERSITY (US) 2023-11-16 WO claimed
US-20230338507-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-26 US claimed
US-20230137914-A1 nOMV-ANTIGEN CONJUGATED COMPOUNDS AND USE THEREOF GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) 2023-05-04 US claimed
CN-115996942-A Macrophage-targeting peptides, conjugates, compositions and uses thereof 双亥生命科学株式会社 2023-04-21 CN claimed
US-11602559-B2 HIV-1 Env fusion peptide immunogens and their use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-03-14 US claimed
EP-4070815-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) 2022-10-12 EP claimed
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS EXELIXIS, INC. 2022-08-18 US claimed
US-20220193244-A1 ANTIMICROBIAL TAILORED CHITOSAN UNIVERSITE DE GENEVE (CH) 2022-06-23 US claimed
WO-2022129926-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2022-06-23 WO claimed
EP-3994150-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS Iconic Therapeutics, Inc. (US) 2022-05-11 EP claimed
CN-114222752-A Anti-tissue factor antibody-drug conjugates and related methods 伊科尼克治疗公司 2022-03-22 CN claimed
EP-1328811-B1 HCV MOSAIC ANTIGEN COMPOSITION MEDMIRA INC (CA) 2005-08-31 EP claimed