SCHEMBL4432965

SCHEMBL4432965

O=C(ON1C(=O)CC(S(=O)(=O)O)C1=O)c1ccc(O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA7 P43166 3/20 0.36
CA9 Q16790 3/20 0.36
CA14 Q9ULX7 3/20 0.36
HPGD P15428 1/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 1/20 0.33
HSP90AA1 P07900 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CHRM1 P11229 1/20 0.32
TSHR P16473 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21167217 0.88 ALDH1A1 (0.38) KMT2AMEN1ALDH1A1TSHRLMNA
SCHEMBL12501894 0.86 ALDH1A1 (0.40) RAB9AALDH1A1
SCHEMBL24393466 0.84 ALDH1A1 (0.44) GAARAB9AHPGDKMT2AMEN1
SCHEMBL15355103 0.82 RIPK1 (0.34) CA1CA2CA9
SCHEMBL13935071 0.81 RIPK1 (0.33) CA1CA2CA9
SCHEMBL6254346 0.80 ALDH1A1 (0.33) GAARAB9AHPGDKMT2AMEN1
SCHEMBL16848723 0.80 KMT2A (0.42) GAARAB9ACA12CA1CA2
SCHEMBL2179698 0.80 ALDH1A1 (0.40) GAARAB9AHPGDKMT2AMEN1
SCHEMBL2239743 0.79 FAAH (0.34) GAAHPGDKMT2AMEN1ESR1
SCHEMBL28976122 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558297-B2 Consumer product with controlled release, biodegradable core-shell microcapsule compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2026-02-24 US disclosed
EP-4557951-A1 COMPOSITION COMPRISING BIODEGRADABLE MICROCAPSULES Givaudan SA (CH) 2025-05-28 EP disclosed
WO-2024017931-A1 COMPOSITION COMPRISING BIODEGRADABLE MICROCAPSULES GIVAUDAN SA (CH) 2024-01-25 WO disclosed
CN-116718644-A Carbon dioxide sensor material and device based on ion conduction gain effect 华南师范大学 2023-09-08 CN disclosed
CN-116622075-A Nano fluorescent temperature indicator and preparation method and application thereof 江苏大学 2023-08-22 CN disclosed
US-20220226797-A1 SUSTAINABLE CORE-SHELL MICROCAPSULES PREPARED WITH COMBINATIONS OF CROSS-LINKERS INT FLAVORS & FRAGRANCES INC (US) 2022-07-21 US disclosed
US-20220175636-A1 CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS INT FLAVORS & FRAGRANCES INC (US) 2022-06-09 US disclosed
US-20220177815-A1 CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS INT FLAVORS & FRAGRANCES INC (US) 2022-06-09 US disclosed
EP-3952824-A1 SUSTAINABLE CORE-SHELL MICROCAPSULES PREPARED WITH COMBINATIONS OF CROSS-LINKERS International Flavors & Fragrances Inc. (US) 2022-02-16 EP disclosed
EP-3952823-A1 CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS International Flavors & Fragrances Inc. (US) 2022-02-16 EP disclosed
EP-3952648-A1 CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS International Flavors & Fragrances Inc. (US) 2022-02-16 EP disclosed
CN-113993499-A Sustainable core-shell microcapsules prepared with a combination of cross-linkers 国际香料和香精公司 2022-01-28 CN disclosed
US-7632816-B2 Treatment of Alzheimer amyloid deposition NEW YORK UNIVERSITY (US) 2009-12-15 US disclosed
US-20040214774-A1 Prevention and treatment of Alzheimer amyloid deposition NEW YORK UNIVERSITY 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220175636-A1 CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS LIPA, LIPE, CAPG GAA 38/4885RAB9A 2265/4885CA12 3645/4885
US-12558297-B2 Consumer product with controlled release, biodegradable core-shell microcapsule compositions LCT, CUTA, LIPE GAA 38/4885RAB9A 4287/4885CA12 2996/4885
US-20220177815-A1 CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS LIPA, MLEC, CHMP4B GAA 229/4885RAB9A 2075/4885CA12 1743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.