Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179698 | 0.88 | ALDH1A1 (0.40) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15080489 | 0.83 | L3MBTL1 (0.43) | L3MBTL1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL10076741 | 0.81 | L3MBTL1 (0.45) | L3MBTL1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL21167217 | 0.78 | ALDH1A1 (0.38) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29382448 | 0.78 | ALDH1A1 (0.38) | L3MBTL1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL16848723 | 0.77 | KMT2A (0.42) | KMT2AALDH1A1SMN1; SMN2MEN1HPGD | |
| SCHEMBL29351152 | 0.75 | GAA (0.41) | L3MBTL1KMT2ATSHRSMN1; SMN2MEN1 | |
| SCHEMBL4289308 | 0.75 | GAA (0.41) | L3MBTL1KMT2ATSHRSMN1; SMN2MEN1 | |
| SCHEMBL9294612 | 0.74 | GAA (0.40) | L3MBTL1KMT2ATSHRSMN1; SMN2MEN1 | |
| SCHEMBL4432965 | 0.72 | GAA (0.36) | KMT2ALMNAALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| US-7815893-B2 | Hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | HACL2, HAAO, LIPA | L3MBTL1 4722/4885KMT2A 4044/4885LMNA 1793/4885 |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | HACL2, HAAO, LIPA | L3MBTL1 4722/4885KMT2A 4044/4885LMNA 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.