Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062014 | 0.78 | ALDH1A1 (0.33) | KMT2A | |
| SCHEMBL18705335 | 0.75 | CYP1A2 (0.35) | TSHRLMNAKMT2A | |
| SCHEMBL3719747 | 0.73 | ALDH1A1 (0.34) | TSHRKMT2A | |
| SCHEMBL29280593 | 0.73 | TSHR (0.54) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL28894956 | 0.73 | TSHR (0.54) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL30080738 | 0.73 | KMT2A (0.32) | KMT2A | |
| SCHEMBL557138 | 0.72 | TSHR (0.40) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL1943663 | 0.72 | TSHR (0.40) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL4942646 | 0.70 | LMNA (0.33) | LMNAKMT2A | |
| Ethylene Glycol SCHEMBL10584826 | 0.69 | ALDH1A1 (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220403329-A1 | Polymeric Carriers and Methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-12-22 | — | — | US | claimed |
| US-20200080051-A1 | Polymeric Carriers and Methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-03-12 | — | — | US | claimed |
| US-11560545-B2 | Polymeric carriers and methods | LONZA WALKERSVILLE INC. (US) | 2023-01-24 | — | — | US | disclosed |
| US-20200080051-A1 | Polymeric Carriers and Methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-03-12 | — | — | US | disclosed |