SCHEMBL217993

SCHEMBL217993

C=C(C(=O)OC12CC3CC(CC(C3)C1)C2)C(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.36
CYP17A1 P05093 5/20 0.36
NAAA Q02083 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
EPHX1 P07099 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD11B1 P28845 1/20 0.31
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
EPHX2 P34913 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678026 0.83 CYP19A1 (0.40) CYP19A1CYP17A1NAAANPSR1EPHX1
SCHEMBL679915 0.77 NPSR1 (0.40) CYP19A1CYP17A1NAAANPSR1ALDH1A1
SCHEMBL677512 0.76 KMT2A (0.45) CYP19A1CYP17A1NAAANPSR1ALDH1A1
SCHEMBL45476 0.74 NAAA (0.40) CYP19A1CYP17A1NAAANPSR1EPHX1
Methacrylic Acid SCHEMBL7096069 0.74 CYP19A1 (0.33) CYP19A1CYP17A1NAAANPSR1
SCHEMBL16369107 0.74 CYP19A1 (0.40) CYP19A1CYP17A1NAAANPSR1EPHX1
SCHEMBL3152890 0.73 CYP19A1 (0.37) CYP19A1CYP17A1NAAANPSR1EPHX1
SCHEMBL27736443 0.73 CYP19A1 (0.44) CYP19A1CYP17A1NAAANPSR1EPHX1
SCHEMBL28138951 0.73 NAAA (0.39) CYP19A1CYP17A1NAAANPSR1EPHX1
SCHEMBL12009911 0.72 CYP19A1 (0.45) CYP19A1CYP17A1NAAANPSR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
EP-2718379-B1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF MERCK PATENT GMBH (DE) 2016-08-17 EP disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
EP-2718379-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ Electronic Materials USA Corp. (US) 2014-04-16 EP disclosed
US-8623589-B2 Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-01-07 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-8455176-B2 Coating composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-06-04 US disclosed
WO-2012168785-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-13 WO disclosed
US-20120308939-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-06 US disclosed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
EP-2384457-A2 COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2011-11-09 EP disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119972-A1 COATING COMPOSITION MERCK PATENT GMBH (DE) 2010-05-13 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
EP-1465877-B1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA (US) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 CYP19A1 4641/4885CYP17A1 3684/4885NAAA 3561/4885
US-20100119972-A1 COATING COMPOSITION S100A9, CAPG, C5 CYP19A1 3787/4885CYP17A1 2459/4885NAAA 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.