SCHEMBL21799667

SCHEMBL21799667

CCC(C)(C)Nc1ccccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.41
GAA P10253 5/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.38
ALOX15 P16050 2/20 0.38
TP53 P04637 1/20 0.38
APP P05067 1/20 0.38
HPGD P15428 1/20 0.38
SNCA P37840 1/20 0.38
BLM P54132 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922535 1.00 MAPT (0.41) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL21799552 0.85 MAPT (0.38) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL21799853 0.84 MAPT (0.41) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL14247353 0.82 MAPT (0.39) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL9806434 0.82 NPSR1 (0.44) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29666932 0.79 MAPT (0.46) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL1269273 0.79 MAPT (0.46) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL19570403 0.78 MAPT (0.54) MAPTGAAKDM4EALDH1A1LMNA
SCHEMBL13727656 0.77 HDAC1 (0.45) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL18826818 0.76 PSIP1 (0.47) GAAKDM4EALDH1A1SMN1; SMN2CCNE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
US-11833122-B2 Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases CALGENT BIOTECHNOLOGY CO., LTD. (TW) 2023-12-05 US disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11833122-B2 Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases KEAP1, GOT2, COL1A1 MAPT 3640/4885GAA 2157/4885KDM4E 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.