SCHEMBL2179989

SCHEMBL2179989

Cc1[c]nc(N(C)C)nc1C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
CREBBP Q92793 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2205728 0.67 LMNA (0.59) LMNACYP1A2THRBBLMCREBBP
SCHEMBL14297683 0.67 LMNA (0.59) LMNACYP1A2THRBBLMCREBBP
SCHEMBL6456004 0.63 LMNA (0.46) LMNACYP1A2THRBBLMCREBBP
SCHEMBL2235435 0.63 LMNA (0.53) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10752491 0.63 LMNA (0.53) LMNACYP1A2THRBBLMCREBBP
SCHEMBL351958 0.62 LMNA (0.38) LMNACYP1A2THRBBLMCREBBP
SCHEMBL351471 0.62 LMNA (0.38) LMNACYP1A2THRBBLMCREBBP
SCHEMBL2267086 0.62 LMNA (0.38) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL2354769 0.61 LMNA (1.00) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL4206 0.61 LMNA (1.00) LMNACYP1A2THRBBLMCREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162906-A1 Pesticide Biomarker NAGY JON OWEN (US) 2014-06-12 US disclosed
US-20110166043-A1 BIOMARKER DETECTION-2 ATERIS TECHNOLOGIES, LLC 2011-07-07 US disclosed
US-20100041077-A1 PESTICIDE BIOMARKER ATERIS TECHNOLOGIES, LLC 2010-02-18 US disclosed
EP-0906014-B1 Shaped bodies which release agrochemicals BAYER AG (DE) 2002-03-27 EP disclosed
US-6329419-B1 CHLORFENAPYR AND SYNERGISTIC AMOUNT OF SUBSTITUTED PHENYLMETHYLCARBAMATE COMPOUND SUCH AS FENOBUCARB, ETHIOFENCARB, ISOPROCARB, METOLCARB, XYLYLCARB, PROPOXUR, CARBARYL, 3,5-XYLYLMETHYCARBAMATE, AND BENDIOCARB AMERICAN CYANAMID CO. 2001-12-11 US disclosed
CN-1044233-C Amide compounds and their salts, processes for their production and pesticidal compositions containing them ISHIHARA SANGYO KAISHA (JP) 1999-07-21 CN disclosed
CN-1081670-A Amide compound and salt thereof, their manufacturing process and pesticide composition thereof ISHIHARA SANGYO KAISHA (JP) 1994-02-09 CN disclosed
EP-0505378-A1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC. (US) 1992-09-30 EP disclosed
EP-0205049-A1 N-benzoyl-N'-(1,1-difluoro-phenylmethyl)-phenyl ureas, processes for their production and their use in pest control BASF Aktiengesellschaft (DE) 1986-12-17 EP disclosed
EP-0124404-A1 Insecticide collar and method for its manufacture Rombi, Max André (FR) 1984-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166043-A1 BIOMARKER DETECTION-2 CPB2, NAALAD2, PRSS2 LMNA 4505/4885CYP1A2 273/4885THRB 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.