Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800147 | 0.85 | CRHBP (0.55) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL8781741 | 0.81 | TRPM8 (0.51) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21800130 | 0.81 | CRHBP (0.51) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL7339073 | 0.79 | ALDH1A1 (0.69) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL350869 | 0.77 | TSHR (0.63) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL522192 | 0.77 | ALDH1A1 (0.64) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL1435066 | 0.77 | CRHBP (0.56) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL21247872 | 0.76 | ALDH1A1 (0.67) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL7999122 | 0.76 | TSHR (0.66) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6956941 | 0.75 | KMT2A (0.56) | CRHBPCRHR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590919-B1 | ENAMINE COMPOUND AND USE THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2024-04-24 | — | — | EP | disclosed |
| US-11773052-B2 | Enamine compound and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2023-10-03 | — | — | US | disclosed |
| US-20200087245-A1 | ENAMINE COMPOUND AND USE THEREOF | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087245-A1 | ENAMINE COMPOUND AND USE THEREOF | ENY2, AHR, PAH | CRHBP 2424/4885CRHR2 844/4885TRPM8 2157/4885 |
| US-11773052-B2 | Enamine compound and use thereof | ENY2, AHR, PAH | CRHBP 2424/4885CRHR2 844/4885TRPM8 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.