Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 7/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583415 | 0.88 | BACE1 (0.37) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL21800783 | 0.87 | BACE1 (0.34) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL1072580 | 0.85 | RAB9A (0.36) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL1083353 | 0.84 | RAB9A (0.36) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL1072471 | 0.84 | RAB9A (0.36) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL3305756 | 0.83 | SLC2A1 (0.33) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL1068681 | 0.78 | KDM4E (0.36) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL29992438 | 0.78 | P2RX3 (0.44) | BACE1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL2434897 | 0.77 | USP30 (0.38) | — | |
| SCHEMBL1072985 | 0.76 | GPR119 (0.34) | BACE1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087265-A1 | HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS | UNIV MASSACHUSETTS (US) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087265-A1 | HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS | HAVCR2, CTSC, DPP4 | BACE1 539/4885KDM4E 782/4885RAB9A 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.