Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | G6PD | P11413 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801756 | 0.87 | NSD2 (0.51) | NSD2G6PDDNMT1XDHADORA1 | |
| SCHEMBL21801766 | 0.83 | NSD2 (0.59) | NSD2G6PDDNMT1ADORA1ADORA2A | |
| SCHEMBL21801902 | 0.82 | XDH (0.41) | XDHADORA1ADORA2AATRDYRK1A | |
| SCHEMBL21801720 | 0.80 | TDP2 (0.48) | NSD2XDHADORA1ADORA2AATR | |
| SCHEMBL21801808 | 0.80 | XDH (0.55) | XDHADORA1ADORA2AATRDYRK1A | |
| SCHEMBL21801780 | 0.77 | NSD2 (0.52) | NSD2G6PDDNMT1ADORA1ADORA2A | |
| SCHEMBL21801735 | 0.76 | NSD2 (0.53) | NSD2G6PDDNMT1UCHL3S100A4 | |
| SCHEMBL21801953 | 0.74 | NSD2 (0.60) | NSD2G6PDDNMT1ADORA1ADORA2A | |
| SCHEMBL21801758 | 0.73 | NSD2 (0.59) | NSD2G6PDDNMT1UCHL3S100A4 | |
| SCHEMBL21801909 | 0.72 | NSD2 (0.52) | NSD2G6PDDNMT1UCHL3S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | disclosed |