Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801782 | 0.81 | SCN5A (0.40) | EPHX2MAPTSCN5AKCNH2SCN9A | |
| SCHEMBL21801743 | 0.80 | MEN1 (0.49) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL630440 | 0.78 | MAPT (0.48) | EPHX2MAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL28624716 | 0.71 | ALDH1A1 (0.35) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL28451946 | 0.71 | — | — | |
| SCHEMBL30448711 | 0.70 | MAPT (0.42) | EPHX2MAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL22404975 | 0.70 | EGFR (0.43) | KCNH2RXRAGRIN1GRIN2BSCN10A | |
| SCHEMBL30091780 | 0.70 | EGFR (0.43) | KCNH2RXRAGRIN1GRIN2BSCN10A | |
| SCHEMBL28780452 | 0.70 | EPHX2 (0.50) | EPHX2MAPTSCN5AKCNH2SCN9A | |
| SCHEMBL15750456 | 0.69 | TRPV4 (0.47) | SCN9ASCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | disclosed |