SCHEMBL630440

SCHEMBL630440

OB(O)Oc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
EPHX2 P34913 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GPR3 P46089 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
MAOB P27338 1/20 0.41
AOC3 Q16853 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
BLM P54132 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
EPAS1 Q99814 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30448711 0.86 MAPT (0.42) MAPTEPHX2L3MBTL1KDM4EGPR3
SCHEMBL5209847 0.83 MAPT (0.45) MAPTEPHX2L3MBTL1KDM4EGPR3
SCHEMBL254957 0.82 MAPT (0.56) MAPTEPHX2L3MBTL1KDM4EGPR3
SCHEMBL3800806 0.82 CA1 (0.38) KMT2AMEN1TSHR
SCHEMBL646662 0.79 TRPV6 (0.52) MAOBAOC3ALDH1A1TSHRTRPV1
SCHEMBL147828 0.79 CA2 (0.52) MAPTEPHX2L3MBTL1KDM4ETSHR
SCHEMBL29151316 0.79 SLC6A2 (0.35) MAPTEPHX2L3MBTL1KDM4EKMT2A
SCHEMBL738580 0.79 ALDH1A1 (0.42) MAPTGPR3ALDH1A1ALOX15TSHR
SCHEMBL21801801 0.78 EPHX2 (0.37) MAPTEPHX2L3MBTL1KMT2AMEN1
Ammonia Solution, Strong SCHEMBL29013463 0.77 TRPV6 (0.50) MAOBAOC3ALDH1A1TSHRTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164477-B Synthesis method of 1, n-dinitrile compound SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2026-05-26 CN disclosed
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN disclosed
CN-120040289-A Method for synthesizing p-nitro trifluoro-methoxybenzene by micro-channel 恒劲生物技术(大连)有限公司 2025-05-27 CN disclosed
CN-113272285-B Oxadiazole-containing compound and pharmaceutical composition containing same 爱思开生物制药株式会社 2024-06-07 CN disclosed
CN-117917400-A 2-Methyl-4-quinolinone compound, and pharmaceutical composition and application thereof 暨南大学 2024-04-23 CN disclosed
CN-117736207-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-03-22 CN disclosed
CN-115362003-B Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-03-22 CN disclosed
CN-117164477-A Synthesis method of 1, n-dinitrile compound 华南理工大学 2023-12-05 CN disclosed
CN-117126152-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-28 CN disclosed
CN-116763791-A Compounds and methods of use thereof 普拉克西斯精密药物股份有限公司 2023-09-19 CN disclosed
US-6172061-B1 AIDS THERAPY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-01-09 US disclosed
US-6166006-A Anilide derivative, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-12-26 US disclosed
WO-2000066568-A1 PESTICIDAL TRIAZINE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2000-11-09 WO disclosed
WO-2000066565-A1 PESTICIDAL PYRIMIDINE-DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2000-11-09 WO disclosed
EP-1039899-A2 PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE Takeda Chemical Industries, Ltd. (JP) 2000-10-04 EP disclosed
EP-1040103-A1 ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-10-04 EP disclosed
WO-2000037455-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-06-29 WO disclosed
WO-1999032100-A2 PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-07-01 WO disclosed
WO-1999032468-A1 ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-07-01 WO disclosed
US-5122297-A For electrooptical displays MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-06-16 US disclosed