Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451946 | 0.79 | — | — | |
| SCHEMBL28702984 | 0.78 | L3MBTL1 (0.53) | MAPTTRPV3L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL2561733 | 0.78 | L3MBTL1 (0.37) | ALDH1A1MAPTTRPV3L3MBTL1KDM4E | |
| SCHEMBL2414188 | 0.76 | KDM4E (0.44) | ALDH1A1MAPTTRPV3L3MBTL1KDM4E | |
| SCHEMBL2185798 | 0.75 | RXRA (0.38) | ALDH1A1MAPTTRPV3L3MBTL1KDM4E | |
| SCHEMBL17253107 | 0.75 | L3MBTL1 (0.40) | ALDH1A1MAPTTRPV3L3MBTL1KDM4E | |
| SCHEMBL26654252 | 0.74 | DGAT1 (0.41) | ALDH1A1MAPTTRPV3L3MBTL1KDM4E | |
| SCHEMBL21801801 | 0.71 | EPHX2 (0.37) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL16908557 | 0.71 | FTO (0.40) | — | |
| SCHEMBL25164045 | 0.71 | RXRA (0.40) | ALDH1A1MAPTTRPV3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272291-A | Pyridazinone compound and use thereof | 艾知怀斯治疗学公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-113272280-A | Pyridazinone compound and use thereof | 艾知怀斯治疗学公司 | 2021-08-17 | — | — | CN | disclosed |