Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.60 |
| ▸ | DRD3 | P35462 | 12/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187147 | 0.84 | DRD2 (0.65) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL21802073 | 0.83 | DRD2 (0.64) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL21802153 | 0.82 | TRPV1 (0.62) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL21802144 | 0.79 | DRD2 (0.63) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL21802158 | 0.79 | DRD3 (0.78) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL5802759 | 0.78 | TRPV1 (0.66) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL16461861 | 0.76 | DRD2 (1.00) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL11261037 | 0.75 | MAPT (0.64) | MAPTSMN1; SMN2GAA | |
| SCHEMBL5732534 | 0.73 | MAPT (0.58) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL8358040 | 0.73 | ALDH1A1 (0.61) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319659-B2 | Selective ligand for dopamine D3 receptor, preparation method therefor, and pharmaceutical application thereof | SHENZHEN LINGLAN BIO-PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-06-03 | — | — | US | claimed |
| US-20200087264-A1 | NOVEL SELECTIVE LIGAND FOR DOPAMINE D3 RECEPTOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | Shenzhen City Linglan Bio-Pharmaceutical Technology Co., Ltd (CN) | 2020-03-19 | — | — | US | claimed |
| US-12319659-B2 | Selective ligand for dopamine D3 receptor, preparation method therefor, and pharmaceutical application thereof | SHENZHEN LINGLAN BIO-PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-06-03 | — | — | US | disclosed |
| US-20200087264-A1 | NOVEL SELECTIVE LIGAND FOR DOPAMINE D3 RECEPTOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | Shenzhen City Linglan Bio-Pharmaceutical Technology Co., Ltd (CN) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087264-A1 | NOVEL SELECTIVE LIGAND FOR DOPAMINE D3 RECEPTOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | DRD3, DRD2, PRLHR | DRD2 2/4885DRD3 1/4885ADRA1A 146/4885 |
| US-12319659-B2 | Selective ligand for dopamine D3 receptor, preparation method therefor, and pharmaceutical application thereof | DRD3, DRD2, PRLHR | DRD2 2/4885DRD3 1/4885ADRA1A 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.