Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933405 | 0.83 | ALDH1A1 (0.61) | ALDH1A1HTTTSHRFAAHSMN1; SMN2 | |
| SCHEMBL2233426 | 0.81 | FAAH (0.48) | ALDH1A1HTTFAAH | |
| SCHEMBL15093778 | 0.81 | MGLL (0.66) | — | |
| SCHEMBL15264489 | 0.81 | MGLL (0.48) | ALDH1A1HTTMAPTHPGDTSHR | |
| SCHEMBL19212181 | 0.78 | KMT2A (0.47) | ALDH1A1MAPTHPGDTSHRNPC1 | |
| SCHEMBL21802533 | 0.78 | PDE2A (0.46) | MEN1KMT2AFAAH | |
| SCHEMBL8250758 | 0.78 | IDO1 (0.50) | ALDH1A1HTTMAPTHPGDTSHR | |
| SCHEMBL28129037 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL21802556 | 0.77 | HTR7 (0.53) | CACNA1GHRH3 | |
| SCHEMBL21618404 | 0.77 | FAAH (0.53) | ALDH1A1HTTTSHRFAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800565-B1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-03-25 | — | — | EP | claimed |