Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | GPR183 | P32249 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802538 | 0.91 | ALDH1A1 (0.53) | BACE1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL20571132 | 0.84 | FAAH (0.65) | BACE1ALDH1A1KDM4EHTTFAAH | |
| SCHEMBL15265082 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHTTPOLB | |
| SCHEMBL15265131 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBFAAHMEN1 | |
| SCHEMBL22365070 | 0.82 | CHKA (0.55) | BACE1ALDH1A1KDM4ELMNA | |
| SCHEMBL15265105 | 0.81 | ALDH1A1 (0.49) | BACE1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL15100943 | 0.81 | MGLL (0.62) | — | |
| SCHEMBL2236430 | 0.81 | GPR183 (0.55) | ALDH1A1KDM4ELMNAHTTPOLB | |
| SCHEMBL21802529 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAHTTPOLB | |
| SCHEMBL21802539 | 0.81 | BACE1 (0.50) | BACE1ALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800565-B1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-03-25 | — | — | EP | claimed |