Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 5/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779746 | 0.85 | CHKA (0.48) | CHKAABCB1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16121936 | 0.83 | CHKA (0.74) | CHKAALDH1A1SLC2A1KDM4E | |
| SCHEMBL21802522 | 0.82 | BACE1 (0.54) | BACE1ALDH1A1LMNAKDM4E | |
| SCHEMBL20198126 | 0.82 | CHKA (0.48) | CHKAMCHR1ABCB1ALDH1A1KDM4E | |
| SCHEMBL15094281 | 0.80 | BACE1 (0.48) | BACE1ABCB1ALDH1A1LMNASLC2A1 | |
| SCHEMBL10819382 | 0.80 | KDM4E (0.70) | BACE1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14986322 | 0.79 | ALDH1A1 (0.68) | MC4RCHRNA7ALDH1A1LMNAKDM4E | |
| SCHEMBL3694689 | 0.79 | CHKA (0.51) | CHKABACE1MC4RCHRNA7ALDH1A1 | |
| SCHEMBL15266145 | 0.79 | BACE1 (0.47) | BACE1ABCB1ALDH1A1LMNAKDM4E | |
| SCHEMBL14924465 | 0.78 | KDM4E (0.50) | CHKAMC4RALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |