Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806190 | 0.93 | MAOB (0.42) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21909036 | 0.88 | MAOB (0.42) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL24012367 | 0.85 | MAOB (0.38) | MAOBAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL21806302 | 0.83 | MAOB (0.52) | MAOBMAOANPC1RXFP1AKR1B10 | |
| Trifluoroacetic Acid SCHEMBL21806084 | 0.80 | MAOB (0.48) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806139 | 0.80 | MAOB (0.48) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806210 | 0.79 | MAOB (0.46) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21909542 | 0.78 | MAOB (0.45) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806750 | 0.76 | BCHE (0.43) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL24012422 | 0.74 | CA12 (0.37) | MAOBMAOANPC1RXFP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |