Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806190 | 0.89 | MAOB (0.42) | MAOBKDM4EALDH1A1CA12CA1 | |
| SCHEMBL24012369 | 0.85 | MAOB (0.45) | MAOBKDM4EALDH1A1HSD17B10CA12 | |
| SCHEMBL21806218 | 0.85 | MAOB (0.45) | MAOBALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL21806248 | 0.84 | CA12 (0.40) | MAOBKDM4EALDH1A1HSD17B10CA12 | |
| SCHEMBL24012362 | 0.84 | ALDH1A1 (0.35) | MAOBKDM4EALDH1A1HSD17B10CA12 | |
| SCHEMBL24012368 | 0.80 | KMT2A (0.45) | MAOBKDM4EALDH1A1HSD17B10CA12 | |
| SCHEMBL21909036 | 0.80 | MAOB (0.42) | MAOBKMT2AAKR1B10AKR1B1 | |
| SCHEMBL21806658 | 0.79 | MAOB (0.33) | MAOBKDM4EALDH1A1HSD17B10CA12 | |
| SCHEMBL15907988 | 0.78 | POLB (0.41) | KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL526532 | 0.77 | HPGD (0.40) | KDM4EALDH1A1HSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |