Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806218 | 0.88 | MAOB (0.45) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806190 | 0.81 | MAOB (0.42) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806302 | 0.80 | MAOB (0.52) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL24012367 | 0.80 | MAOB (0.38) | MAOBAKR1B10AKR1B1KMT2A | |
| SCHEMBL21806139 | 0.76 | MAOB (0.48) | MAOBMAOANPC1RXFP1AKR1B10 | |
| Trifluoroacetic Acid SCHEMBL21806084 | 0.76 | MAOB (0.48) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806210 | 0.76 | MAOB (0.46) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21909542 | 0.74 | MAOB (0.45) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806750 | 0.73 | BCHE (0.43) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL24012422 | 0.71 | CA12 (0.37) | MAOBMAOANPC1RXFP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |