Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806222 | 0.93 | ALDH1A1 (0.48) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806750 | 0.90 | BCHE (0.43) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806302 | 0.86 | MAOB (0.52) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806228 | 0.85 | AKR1B10 (0.59) | NPC1AKR1B10AKR1B1ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL21806084 | 0.84 | MAOB (0.48) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL21806218 | 0.80 | MAOB (0.45) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL15065835 | 0.79 | MAOB (0.57) | MAOBMAOAALDH1A1KDM4EGLA | |
| SCHEMBL21806210 | 0.77 | MAOB (0.46) | MAOBMAOANPC1RXFP1AKR1B10 | |
| SCHEMBL15065793 | 0.77 | MAOB (0.50) | MAOBMAOAALDH1A1KDM4EGLA | |
| SCHEMBL21806085 | 0.76 | MAOB (0.44) | MAOBMAOANPC1RXFP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |
| CN-113423698-A | Coumarin-based crosslinking agents | 文塔纳医疗系统公司 | 2021-09-21 | — | — | CN | disclosed |
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |