Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21807256 | 0.84 | MEN1 (0.45) | ALDH1A1KDM4ETSHRSMN1; SMN2POLB | |
| SCHEMBL21522001 | 0.78 | SIGMAR1 (0.44) | ALDH1A1HTTSIGMAR1 | |
| SCHEMBL31158622 | 0.78 | SIGMAR1 (0.44) | ALDH1A1HTTSIGMAR1 | |
| SCHEMBL4525709 | 0.75 | SIGMAR1 (0.44) | ALDH1A1KDM4ESIGMAR1ATM | |
| SCHEMBL21522072 | 0.71 | KMT2A (0.47) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPK1 | |
| SCHEMBL4224502 | 0.70 | SIGMAR1 (0.46) | KDM4ESIGMAR1L3MBTL1 | |
| SCHEMBL21807201 | 0.69 | USP30 (0.40) | SMN1; SMN2POLBMEN1MAPK1KMT2A | |
| SCHEMBL30309419 | 0.68 | PTGS2 (0.40) | ALDH1A1KDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL9757304 | 0.67 | PARP1 (0.46) | MEN1KMT2A | |
| SCHEMBL31158897 | 0.67 | CYP1A2 (0.38) | ALDH1A1TSHRTDP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3852790-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | Forma Therapeutics, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020061261-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |