Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357344 | 1.00 | ADRB1 (0.41) | ADRB1CA12CA1CA2CA9 | |
| SCHEMBL20353917 | 0.81 | ABL1 (0.44) | CA12CA1CA2CA9ABL1 | |
| SCHEMBL31357331 | 0.79 | TSHR (0.61) | TSHRALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9191562 | 0.79 | TSHR (0.61) | TSHRALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL14774791 | 0.75 | TSHR (0.65) | TSHRKDM4EALDH1A1RAB9AEGFR | |
| SCHEMBL16113133 | 0.73 | TSHR (0.38) | ADRB1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9191455 | 0.73 | TDP1 (0.63) | TSHRALDH1A1HTTRAB9A | |
| SCHEMBL31165861 | 0.73 | AR (0.48) | KDM4EMEN1KMT2AHSD17B10HTT | |
| SCHEMBL30008156 | 0.73 | RAB9A (0.67) | ALDH1A1RAB9A | |
| SCHEMBL18172092 | 0.73 | CA12 (0.41) | CA12CA1CA2CA9ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12110299-B2 | Thiazole derivatives and pharmaceutically acceptable salts thereof | YUNGJIN PHARM. CO., LTD. (KR) | 2024-10-08 | — | — | US | disclosed |
| EP-3853225-B1 | N-(5-(3-(1-((THIAZOL-2-YL)AMINO)-1-OXOPROPAN-2-YL)PHENYL)PYRIDIN-2-YL)ACRYLAMIDE DERIVATIVES AS CDK7 INHIBITORS FOR THE TREATMENT OF CANCER | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2023-11-29 | — | — | EP | disclosed |
| US-20210284658-A1 | NOVEL THIAZOLE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | YUNGJIN PHARM. CO., LTD. (KR) | 2021-09-16 | — | — | US | disclosed |
| EP-3853225-A1 | NOVEL THIAZOLE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Yungjin Pharm. Co., Ltd. (KR) | 2021-07-28 | — | — | EP | disclosed |
| CN-112739695-A | Novel thiazole derivative and pharmaceutically acceptable salt thereof | 永进药品工业株式会社 | 2021-04-30 | — | — | CN | disclosed |
| WO-2020060112-A1 | NOVEL THIAZOLE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | YUNGJIN PHARM. CO., LTD. (KR) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284658-A1 | NOVEL THIAZOLE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | CDKL1, CDKL3, CDKL2 | ADRB1 4075/4885CA12 3933/4885CA1 3639/4885 |
| US-12110299-B2 | Thiazole derivatives and pharmaceutically acceptable salts thereof | CDKL1, CDK4, CDKL3 | ADRB1 4161/4885CA12 3739/4885CA1 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.