Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191562 | 1.00 | TSHR (0.61) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL18172092 | 0.81 | CA12 (0.41) | TSHRRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9191455 | 0.81 | TDP1 (0.63) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31165861 | 0.81 | AR (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15004187 | 0.80 | TSHR (0.69) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL21808421 | 0.79 | ADRB1 (0.41) | TSHRRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL31357344 | 0.79 | ADRB1 (0.41) | TSHRRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7936077 | 0.79 | TSHR (0.67) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7030047 | 0.79 | RAB9A (0.72) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL27886032 | 0.79 | TSHR (0.77) | TSHRRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739695-B | Novel thiazole derivative and pharmaceutically acceptable salt thereof | 永进药品工业株式会社 | 2025-03-18 | — | — | CN | disclosed |