SCHEMBL21808798

SCHEMBL21808798

CCCC[Sn](CCCC)(CCCC)c1cncc(-c2cccnc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.49
CYP19A1 P11511 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2A6 P11509 6/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PPARA Q07869 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
EPHX2 P34913 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
CYP2E1 P05181 1/20 0.39
CYP2B6 P20813 1/20 0.39
TLR8 Q9NR97 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2646328 0.88 CYP19A1 (0.49) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL1180536 0.88 CYP3A4 (0.38) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL9171223 0.85 CYP3A4 (0.59) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL29851135 0.82 L3MBTL1 (0.49) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL154603 0.82 L3MBTL1 (0.49) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL28083685 0.81 MKNK1 (0.35) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL4317264 0.75 L3MBTL1 (0.41) CYP3A4CYP19A1CYP2C9CYP2C19CYP2D6
SCHEMBL12502235 0.74 CHRNB2 (0.33)
SCHEMBL28083647 0.74 CA2 (0.43) CYP11B2
SCHEMBL5733424 0.73 HCAR2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11815475-B2 Method for identifying molecular structure THE UNIVERSITY OF TOKYO (JP) 2023-11-14 US disclosed
EP-3591387-B1 METHOD FOR IDENTIFYING MOLECULAR STRUCTURE UNIV TOKYO (JP) 2023-09-27 EP disclosed
US-20200096461-A1 METHOD FOR IDENTIFYING MOLECULAR STRUCTURE THE UNIVERSITY OF TOKYO (JP) 2020-03-26 US disclosed