Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29851135 | 1.00 | L3MBTL1 (0.49) | L3MBTL1TDP1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4317264 | 0.91 | L3MBTL1 (0.41) | L3MBTL1TDP1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL21808798 | 0.82 | CYP3A4 (0.49) | L3MBTL1TDP1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2646328 | 0.82 | CYP19A1 (0.49) | L3MBTL1TDP1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9171223 | 0.82 | CYP3A4 (0.59) | L3MBTL1TDP1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL155502 | 0.76 | HRH3 (0.31) | HDAC3HDAC1HDAC2 | |
| SCHEMBL658276 | 0.76 | CYP2D6 (0.41) | L3MBTL1TDP1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL276811 | 0.76 | LTA4H (0.38) | TDP1TSHRKMT2AMEN1 | |
| SCHEMBL28275 | 0.76 | LOXL2 (0.32) | L3MBTL1TDP1 | |
| SCHEMBL1456734 | 0.74 | MAPT (0.38) | L3MBTL1TDP1CYP2C19HDAC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528815-B2 | 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer | NXERA PHARMA UK LIMITED (GB) | 2026-01-20 | — | — | US | disclosed |
| US-20250388531-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-12-25 | — | — | US | disclosed |
| WO-2025110699-A1 | NOVEL COMPOUND AND USE THEREOF | 주식회사 프로티어바이오텍 | 2025-05-30 | — | — | WO | disclosed |
| US-20240400555-A1 | Compounds, Compositions and Methods for Attenuation of Mammalian Translation of C-MYC or N-MYC Proteins of the MYC Proto-Oncogene Family of BHLH Transcription Factors | INITIAL THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | US | disclosed |
| WO-2024226875-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR ATTENUATION OF MAMMALIAN TRANSLATION OF C-MYC OR N-MYC PROTEINS OF THE MYC PROTO-ONCOGENE FAMILY OF BHLH TRANSCRIPTION FACTORS | INITIAL THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-117561262-A | Macrocyclic TAK1 inhibitors | 阿奎利恩有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117510503-A | Tyrosine threonine kinase PKMYT1 inhibitor | 成都先导药物开发股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | disclosed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-116368133-A | NLRX1 ligand | 朗多生物制药股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-5493029-A | USEFUL IN TREATING ASTHMA AND HYPERTENSION | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-02-20 | — | — | US | disclosed |
| WO-1995034564-A1 | PIRYDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995021838-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-08-17 | — | — | WO | disclosed |
| EP-0360369-B1 | 11-Beta-phenyl-14-beta-H-steroids | SCHERING AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| US-5244886-A | Antitumor, oxytocics, contraceptives | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | disclosed |
| EP-0514942-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0506363-A1 | 6-Heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles | ELI LILLY AND COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| EP-0506369-A1 | 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[CD]indoles | ELI LILLY AND COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| EP-0430129-A2 | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990003385-A1 | 11β-PHENYL-14βH-STEROIDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388531-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | TET1, TET3, TRRAP | L3MBTL1 977/4885TDP1 1572/4885CYP2C9 334/4885 |
| US-20240400555-A1 | Compounds, Compositions and Methods for Attenuation of Mammalian Translation of C-MYC or N-MYC Proteins of the MYC Proto-Oncogene Family of BHLH Transcription Factors | MYCBP, MYC, MYCBP2 | L3MBTL1 1065/4885TDP1 3636/4885CYP2C9 4710/4885 |
| US-12528815-B2 | 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer | ADORA1, ADORA3, OPRL1 | L3MBTL1 2126/4885TDP1 615/4885CYP2C9 2370/4885 |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | KDM5C, KDM5B, KDM5A | L3MBTL1 820/4885TDP1 570/4885CYP2C9 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.