Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811034 | 1.00 | PIK3CD (0.43) | PIK3CDPIK3CAPAK1MDM2HSD11B1 | |
| SCHEMBL31171017 | 0.85 | PIK3CD (0.51) | PIK3CDPIK3CAHSD11B1CYP3A4CYP2D6 | |
| SCHEMBL29124439 | 0.85 | PIK3CD (0.51) | PIK3CDPIK3CAHSD11B1CYP3A4CYP2D6 | |
| SCHEMBL7178421 | 0.85 | PIK3CD (0.51) | PIK3CDPIK3CAHSD11B1CYP3A4CYP2D6 | |
| SCHEMBL7178416 | 0.85 | PIK3CD (0.51) | PIK3CDPIK3CAHSD11B1CYP3A4CYP2D6 | |
| SCHEMBL23236169 | 0.83 | HSD11B1 (0.49) | PIK3CDPIK3CAPAK1HSD11B1CYP3A4 | |
| SCHEMBL23236166 | 0.83 | HSD11B1 (0.49) | PIK3CDPIK3CAPAK1HSD11B1CYP3A4 | |
| SCHEMBL21811243 | 0.82 | PAK1 (0.41) | PIK3CDPIK3CAPAK1CCNKCDK12 | |
| SCHEMBL21811241 | 0.82 | PAK1 (0.41) | PIK3CDPIK3CAPAK1CCNKCDK12 | |
| SCHEMBL27233778 | 0.81 | CDK12 (0.56) | HSD11B1CYP3A4CYP2D6CYP2C9CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206765-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-07-08 | — | — | US | disclosed |
| EP-3808747-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020054788-A1 | IMIDAZOPYRIDINONE COMPOUND | キッセイ薬品工業株式会社 | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206765-A1 | IMIDAZOPYRIDINONE COMPOUND | DHPS, EGLN3, P4HA1 | PIK3CD 3067/4885PIK3CA 2929/4885PAK1 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.