SCHEMBL21815744

SCHEMBL21815744

O=C(Cl)c1cc2ccccc2c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
TRPM4 Q8TD43 1/20 0.48
ALDH1A1 P00352 6/20 0.45
KDM4E B2RXH2 4/20 0.45
HPGD P15428 3/20 0.45
CYP1A2 P05177 2/20 0.45
HSD17B10 Q99714 2/20 0.45
GLA P06280 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 1/20 0.45
CYP1B1 Q16678 2/20 0.44
CYP1A1 P04798 1/20 0.44
PAX8 Q06710 1/20 0.43
GPR35 Q9HC97 2/20 0.43
POLB P06746 1/20 0.43
HIF1A Q16665 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50624 0.83 ALDH1A1 (0.56) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL31529060 0.83 HPGD (0.53) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL23698266 0.81 MEN1 (0.51) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL522958 0.81 MEN1 (0.71) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL9062637 0.80 HPRT1 (0.54) ALDH1A1HPGDHSD17B10PAX8MAPT
SCHEMBL31424059 0.80 ALDH1A1 (0.52) MEN1KMT2ARXFP1TRPM4ALDH1A1
SCHEMBL2154152 0.80 ALDH1A1 (0.44) MEN1KMT2ARXFP1ALDH1A1KDM4E
SCHEMBL3914053 0.80 CDC25B (0.60) MEN1KMT2ATRPM4ALDH1A1KDM4E
SCHEMBL29752028 0.80 ALDH1A1 (0.50) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL1958554 0.80 ALDH1A1 (0.50) MEN1KMT2AALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111247648-B Heterocyclic compound and organic light-emitting device comprising the same LT素材株式会社 2023-09-15 CN disclosed
US-11678576-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2023-06-13 US disclosed
US-11678576-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2023-06-13 US disclosed
US-11476425-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-10-18 US disclosed
EP-3858831-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LT Materials Co., Ltd. (KR) 2021-08-04 EP disclosed
US-20210226133-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT Materials Co., Ltd (KR) 2021-07-22 US disclosed
US-20210202863-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2021-07-01 US disclosed
WO-2021015497-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-01-28 WO disclosed
CN-111247648-A Heterocyclic compound and organic light-emitting device comprising the same 喜星素材株式会社 2020-06-05 CN disclosed
WO-2020067593-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 희성소재(주) 2020-04-02 WO disclosed
WO-2020067594-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 희성소재(주) 2020-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210202863-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 MEN1 351/4885KMT2A 592/4885RXFP1 3678/4885
US-20210226133-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 MEN1 351/4885KMT2A 592/4885RXFP1 3678/4885
US-11476425-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 MEN1 351/4885KMT2A 592/4885RXFP1 3678/4885
US-11678576-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 MEN1 351/4885KMT2A 592/4885RXFP1 3678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.