SCHEMBL2154152

SCHEMBL2154152

O=C(Cl)c1cc(C(=O)Cl)c2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
HPGD P15428 2/20 0.44
PTPN1 P18031 2/20 0.44
MAPT P10636 1/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 2/20 0.42
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
CYP1A2 P05177 1/20 0.42
GLA P06280 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CDC25B P30305 3/20 0.40
ALOX15 P16050 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MMP3 P08254 1/20 0.39
HDAC8 Q9BY41 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348226 0.82 PTPN1 (0.42) ALDH1A1HPGDPTPN1MAPTALOX15
SCHEMBL3914053 0.81 CDC25B (0.60) ALDH1A1HPGDPTPN1MAPTMEN1
SCHEMBL27514568 0.81 NQO2 (0.53) ALDH1A1HPGDPTPN1MAPTMEN1
SCHEMBL21815744 0.80 MEN1 (0.50) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL2154228 0.79 PTPN1 (0.61) ALDH1A1HPGDPTPN1MAPTMEN1
SCHEMBL15591156 0.79 MEN1 (0.46) ALDH1A1HPGDPTPN1MEN1KMT2A
SCHEMBL31625685 0.79 PTPN1 (0.61) ALDH1A1HPGDPTPN1MAPTMEN1
SCHEMBL14829422 0.78 PTPN1 (0.54) ALDH1A1HPGDPTPN1MAPTMEN1
SCHEMBL15591078 0.78 PTGER4 (0.51) ALDH1A1HPGDPTPN1MAPTMEN1
SCHEMBL18153975 0.78 CES2 (0.50) ALDH1A1HPGDPTPN1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110591083-B Polyamide high polymer material based on 2, 5-diallyloxy p-phenylenediamine monomer and preparation method thereof 北京大学 2020-11-10 CN disclosed
CN-106661245-B Method for producing film and method for storing coating liquid 住友化学株式会社 2020-08-21 CN disclosed
US-10730819-B2 Naphthalenedicarboxylic acid dichloride production method KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-08-04 US disclosed
CN-111039779-A Process for producing naphthalenedicarboxylic dichloride 京瓷办公信息系统株式会社 2020-04-21 CN disclosed
US-20200115313-A1 NAPHTHALENEDICARBOXYLIC ACID DICHLORIDE PRODUCTION METHOD KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-16 US disclosed
CN-110591083-A Novel polyamide high polymer material based on 2, 5-diallyloxy p-phenylenediamine monomer and preparation method thereof 北京大学 2019-12-20 CN disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
US-20170305945-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-10-26 US disclosed
US-9732106-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-08-15 US disclosed
CN-104611806-A Flame retardant yarn comprising aromatic polymer fiber containing sulfuryl, fabric made of same and preparation method SHANGHAI TANLON FIBER CO LTD 2015-05-13 CN disclosed
CN-104611804-A Yarn and fabric made by sulfonyl-containing aromatic polymer fibers and high-temperature-resistant flame-retardant fibers and preparation methods SHANGHAI TANLON FIBER CO LTD 2015-05-13 CN disclosed
CN-104611835-A Flocculus comprising aromatic polymer fiber containing sulfuryl and preparation method thereof SHANGHAI TANLON FIBER CO LTD 2015-05-13 CN disclosed
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-08-07 US disclosed
US-8680003-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-03-25 US disclosed
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-06 US disclosed
EP-2519532-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS Chevron Phillips Chemical Company LP (US) 2012-11-07 EP disclosed
WO-2011082192-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-07-07 WO disclosed
EP-0402670-A2 Method for preparing cyclic polyarylate oligomers GENERAL ELECTRIC COMPANY (US) 1990-12-19 EP disclosed
US-4927904-A REACTING AN AROMATIC DICARBOXYLIC ACID HALIDE AND A DIHYDROXAROMATIC SALT; QUATERNARY AMMONIA SALT GENERAL ELECTRIC COMPANY (US) 1990-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 ALDH1A1 4849/4885HPGD 3570/4885PTPN1 1741/4885
US-20200115313-A1 NAPHTHALENEDICARBOXYLIC ACID DICHLORIDE PRODUCTION METHOD DDT, DHODH, DLD ALDH1A1 786/4885HPGD 45/4885PTPN1 4001/4885
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 ALDH1A1 4849/4885HPGD 3570/4885PTPN1 1741/4885
US-10730819-B2 Naphthalenedicarboxylic acid dichloride production method DDT, DHODH, DLD ALDH1A1 786/4885HPGD 45/4885PTPN1 4001/4885
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 ALDH1A1 4849/4885HPGD 3570/4885PTPN1 1741/4885
US-20170305945-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 ALDH1A1 4849/4885HPGD 3570/4885PTPN1 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.