Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15883236 | 0.88 | CA12 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19RAPGEF4 | |
| SCHEMBL11219354 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TAAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8014673 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CXCR2CYP3A4RAPGEF4GAA | |
| SCHEMBL16001849 | 0.81 | TAAR1 (0.51) | TAAR1 | |
| SCHEMBL15883199 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TAAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24318169 | 0.78 | ALDH1A1 (0.62) | ALDH1A1CXCR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11664862 | 0.76 | TAAR1 (0.49) | ALDH1A1TAAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11541393 | 0.76 | HTT (0.54) | CXCR2KMT2AKCNK3KCNK9CA12 | |
| SCHEMBL2927671 | 0.76 | POLB (0.56) | ALDH1A1CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL29999663 | 0.76 | POLB (0.56) | ALDH1A1CYP1A2CYP3A4CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | ALDH1A1 731/4885TAAR1 1550/4885CXCR2 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.