Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | CTSD | P07339 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193357 | 0.82 | OPRD1 (0.56) | OPRD1OPRM1OPRK1CTSD | |
| SCHEMBL2193363 | 0.82 | OPRD1 (0.56) | OPRD1OPRM1OPRK1CTSD | |
| SCHEMBL3863306 | 0.81 | OPRD1 (0.57) | OPRD1OPRM1OPRK1CTSD | |
| SCHEMBL28201639 | 0.80 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL30052420 | 0.79 | CTSD (0.55) | OPRD1OPRM1OPRK1CTSD | |
| SCHEMBL6320406 | 0.79 | CTSC (0.63) | — | |
| SCHEMBL3497465 | 0.79 | CTSC (0.63) | — | |
| SCHEMBL2182294 | 0.79 | OPRD1 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL238636 | 0.78 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4088898 | 0.78 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | OPRD1 3100/4885OPRM1 2317/4885OPRK1 2737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.