Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241107 | 1.00 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 | |
| SCHEMBL2191632 | 0.89 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL11286107 | 0.87 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29721310 | 0.85 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL11246910 | 0.85 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29549215 | 0.85 | OPRD1 (0.88) | OPRD1OPRM1OPRK1 | |
| Biphalin SCHEMBL29582936 | 0.85 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL11053897 | 0.85 | OPRD1 (0.88) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8893265 | 0.84 | CTSC (0.67) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9143188 | 0.84 | CTSC (0.67) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877891-B2 | Method of producing a novel opioid peptide | LIPKOWSKI ANDREJ (PL) | 2014-11-04 | — | — | US | claimed |
| EP-2384334-B1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEV OF RESARCH SP Z O O (PL) | 2013-02-27 | — | — | EP | claimed |
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | LIPKOWSKI ANDREJ (PL) | 2012-01-05 | — | — | US | claimed |
| EP-2384334-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | Action For Development Of Resarch SP.Z.O.O. (PL) | 2011-11-09 | — | — | EP | claimed |
| WO-2010077154-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEVELOPMENT OF RESARCH SP.Z.O.O. (PL) | 2010-07-08 | — | — | WO | claimed |
| EP-0030846-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | claimed |
| US-8877891-B2 | Method of producing a novel opioid peptide | LIPKOWSKI ANDREJ (PL) | 2014-11-04 | — | — | US | disclosed |
| EP-2384334-B1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEV OF RESARCH SP Z O O (PL) | 2013-02-27 | — | — | EP | disclosed |
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | LIPKOWSKI ANDREJ (PL) | 2012-01-05 | — | — | US | disclosed |
| EP-2384334-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | Action For Development Of Resarch SP.Z.O.O. (PL) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010077154-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEVELOPMENT OF RESARCH SP.Z.O.O. (PL) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | OPRL1, OPRK1, OGFR | OPRD1 5/4885OPRM1 4/4885OPRK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.