SCHEMBL3863306

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)NCC(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.57

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	15/20	0.57

▸	OPRM1	P35372	11/20	0.57

▸	OPRK1	P41145	2/20	0.57

▸	CTSD	P07339	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31411848	0.92	CTSD (0.54)	OPRD1OPRM1OPRK1CTSD
SCHEMBL3209858	0.90	OPRD1 (0.54)	OPRD1OPRM1OPRK1CTSD
SCHEMBL30050825	0.86	OPRD1 (0.53)	OPRD1OPRM1OPRK1CTSD
SCHEMBL29351955	0.84	CTSD (0.57)	OPRD1OPRM1CTSD
SCHEMBL29720334	0.83	CTSD (0.53)	OPRD1OPRM1OPRK1CTSD
SCHEMBL30051265	0.83	CTSD (0.53)	OPRD1OPRM1OPRK1CTSD
SCHEMBL31215118	0.83	OPRD1 (0.65)	OPRD1OPRM1OPRK1
SCHEMBL11060666	0.81	OPRD1 (0.78)	OPRD1OPRM1OPRK1
SCHEMBL11060658	0.81	OPRD1 (0.78)	OPRD1OPRM1OPRK1
SCHEMBL2181844	0.81	OPRD1 (0.52)	OPRD1OPRM1OPRK1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2040758-A2	BIORESPONSIVE POLYMERS	Interface Biologics Inc. (CA)	2009-04-01	—	—	EP	disclosed
WO-2008053362-A2	BIORESPONSIVE POLYMERS	INTERFACE BIOLOGICS, INC. (CA)	2008-05-08	—	—	WO	disclosed