SCHEMBL218212

SCHEMBL218212

c1ccc(C2NCCO2)c(C2NCCO2)c1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.46
ADRA1A P35348 1/20 0.46
HTR2B P41595 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ALDH1A1 P00352 1/20 0.43
DRD3 P35462 3/20 0.39
CHRNA7 P36544 1/20 0.38
DRD2 P14416 2/20 0.36
PRCP P42785 2/20 0.34
GAA P10253 1/20 0.33
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19066793 0.90 SLC6A2 (0.42) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL7380979 0.86 HTR2C (0.46) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL3655084 0.86 HTR2B (0.40) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL7220765 0.86 SLC6A2 (0.40) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL11493571 0.86 SLC6A2 (0.40) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL10791720 0.83 KDM1A (0.43) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL7638483 0.83 ADRA2A (0.43) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL12155157 0.82 ALDH1A1 (0.56) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL460150 0.80 SLC6A2 (0.58) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1
SCHEMBL2257666 0.80 SLC6A2 (0.58) SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252572-B2 Method for improving adhesion in and between layers of additive manufactured articles LUMAS POLYMERS LLC (US) 2025-03-18 US claimed
EP-3131946-B1 METHOD FOR MANUFACTURING A THERMOPLASTIC MATERIAL MADE FROM SEMI-CRYSTALLINE POLYAMIDE ARKEMA FRANCE (FR) 2023-11-22 EP claimed
US-20230097954-A1 METHOD FOR IMPROVING ADHESION IN AND BETWEEN LAYERS OF ADDITIVE MANUFACTURED ARTICLES LUMAS POLYMERS LLC 2023-03-30 US claimed
EP-4110618-A1 METHOD FOR IMPROVING ADHESION IN AND BETWEEN LAYERS OF ADDITIVE MANUFACTURED ARTICLES Jabil Inc. (US) 2023-01-04 EP claimed
EP-4101875-A1 POLYMERIC POLYOXAZOLINES PPG Industries Ohio, Inc. (US) 2022-12-14 EP claimed
EP-3724256-B1 POLYMERIC POLYOXAZOLINES PPG IND OHIO INC (US) 2022-06-08 EP claimed
EP-3325538-B1 SEMI-CRYSTALLINE POLYAMIDE COMPOSITION HAVING A HIGH GLASS TRANSITION TEMPERATURE FOR A COMPOSITE MATERIAL, PRODUCTION METHOD THEREOF AND USES OF SAME ARKEMA FRANCE (FR) 2021-03-03 EP claimed
EP-3724256-A1 POLYMERIC POLYOXAZOLINES PPG Industries Ohio Inc. (US) 2020-10-21 EP claimed
CN-111448240-A Polymeric polyoxazolines PPG工业俄亥俄公司 2020-07-24 CN claimed
US-10377856-B2 Semi-crystalline polyamide composition with high glass transition temperature for composite material, process for manufacturing same and uses thereof ARKEMA FRANCE (FR) 2019-08-13 US claimed
US-20040219367-A1 Low-temperature-curable, solid polyurethane powder coating compositions containing uretdione groups DEGUSSA AG (DE) 2004-11-04 US claimed
US-20030153713-A1 Low-temperature-curable, solid polyurethane powder coating compositions containing uretdione groups DEGUSSA AG (DE) 2003-08-14 US claimed
EP-1334987-A2 Low temperature curable solid powder lacquer compositions containing urethdione groups Degussa AG (DE) 2003-08-13 EP claimed
EP-0611805-B1 Housing for electronic equipment made of a polyamide resin composition FUJITSU LTD (JP) 1998-04-15 EP claimed
US-5631070-A MOLDED PRODUCT CONTAINING AROMATIC POLYAMIDE, POLYPHENYLENE ETHER MODIFIED WITH UNSATURATED ALIPHATIC CARBOXYLIC ACID OR ANHYDRIDE, LIQUID CRYSTALLINE COPOLYESTER, PHENYLENEBISOXAZOLINE, INORGANIC FILLER FUJITSU LIMITED (JP) 1997-05-20 US claimed
EP-0438128-B1 Polymer blend composition for melt molding UNITIKA LTD (JP) 1996-05-29 EP claimed
US-5470909-A Polyphenylene ether modified with unsaturated acid and liquid crystal polyester FUJITSU LIMITED (JP) 1995-11-28 US claimed
US-5324795-A Thickener added to a liquid crystal and non liquid crystal UNITIKA LTD. (JP) 1994-06-28 US claimed
US-5173357-A Tear-resistant polyester film and laminated sheets comprised of the same POLYPLASTICS CO., LTD. (JP) 1992-12-22 US claimed
EP-0438128-A2 Polymer blend composition for melt molding UNITIKA LTD. (JP) 1991-07-24 EP claimed