Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218212 | 0.86 | SLC6A2 (0.46) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL19066793 | 0.81 | SLC6A2 (0.42) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL7220765 | 0.78 | SLC6A2 (0.40) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL3655084 | 0.78 | HTR2B (0.40) | HTR2CHTR2BSLC6A2SLC6A3ADRA1A | |
| SCHEMBL11493571 | 0.78 | SLC6A2 (0.40) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL12155157 | 0.77 | ALDH1A1 (0.56) | HTR2CHTR2BSLC6A2SLC6A3ADRA1A | |
| SCHEMBL10791720 | 0.75 | KDM1A (0.43) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL7638483 | 0.75 | ADRA2A (0.43) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL2257666 | 0.72 | SLC6A2 (0.58) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 | |
| SCHEMBL460150 | 0.72 | SLC6A2 (0.58) | HTR2BSLC6A2SLC6A3ADRA1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309690-A | Chemokine receptor binding compounds | ANORMED INC (CA) | 2008-11-19 | — | — | CN | disclosed |
| WO-2000076484-A1 | PHARMACEUTICAL PREPARATION WITH DELAYED RELEASE OF AN ACTIVE SUBSTANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | disclosed |