SCHEMBL460150

SCHEMBL460150

c1ccc(C2NCCO2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.58
SLC6A3 Q01959 2/20 0.58
ADRA1A P35348 1/20 0.58
HTR2B P41595 1/20 0.58
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.43
CHRNA7 P36544 1/20 0.41
TACR1 P25103 8/20 0.40
SLC18A3 Q16572 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
CYP2D6 P10635 1/20 0.38
SLC6A4 P31645 1/20 0.38
KCNH2 Q12809 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
PRCP P42785 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2257666 1.00 SLC6A2 (0.58) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL1023795 0.89 ALDH1A1 (0.59) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL4518432 0.86 SLC6A2 (0.44) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL594796 0.85 ALDH1A1 (0.57) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL16884713 0.84 ALDH1A1 (0.45) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL218212 0.80 SLC6A2 (0.46) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL16884718 0.80 ALDH1A1 (0.46) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL3655086 0.79 ALDH1A1 (0.51) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL10795916 0.79 CHRNA7 (0.59) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1
SCHEMBL8117490 0.79 ALDH1A1 (0.47) SLC6A2SLC6A3ADRA1AHTR2BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025216834-A1 AQUEOUS DISPERSION OF POLYMER PARTICLES AND ORGANIC OPACIFYING PIGMENT PARTICLES ROHM AND HAAS COMPANY (US) 2025-10-16 WO claimed
CN-116332710-B Preparation method of metal-catalyzed benzyl ether and prepared benzyl ether 合肥工业大学 2024-11-26 CN claimed
CN-116332710-A Preparation method of metal-catalyzed benzyl ether and prepared benzyl ether 合肥工业大学 2023-06-27 CN claimed
EP-3635062-B1 A METHOD FOR PREVENTING HARDENER COMPOUNDS TO BE FORMED FROM HARDENER PRECURSORS AND EXTENDING SHELF LIFE OF THE DISPERSION WISESPRAY INT OY (FI) 2022-03-02 EP claimed
EP-2604619-A2 Mannose derivatives as antagonists of bacterial adhesion University of Basel (CH) 2013-06-19 EP claimed
WO-2012164074-A1 MANNOSE PHOSPHATE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION UNIVERSITY OF BASEL (CH) 2012-12-06 WO claimed
US-20120270824-A1 MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION UNIVERSITY OF BASEL (CH) 2012-10-25 US claimed
EP-2513128-A2 MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION University of Basel (CH) 2012-10-24 EP claimed
WO-2011073112-A2 MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION UNIVERSITY OF BASEL (CH) 2011-06-23 WO claimed
US-6632813-B1 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both KYORIN PHARMACEUTICAL CO., LTD. (JP) 2003-10-14 US claimed
EP-1341761-A1 SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-$g(g) BINDING AGENTS SMITHKLINE BEECHAM CORPORATION (US) 2003-09-10 EP claimed
US-20030087902-A1 Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents SMITHKLINE BEECHAM CORPORATION 2003-05-08 US claimed
WO-2002030895-A1 SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-η BINDING AGENTS SMITHKLINE BEECHAM CORPORATION (US) 2002-04-18 WO claimed
JP-57130969-A None JP disclosed
JP-54125663-A None JP disclosed
WO-2025216834-A1 AQUEOUS DISPERSION OF POLYMER PARTICLES AND ORGANIC OPACIFYING PIGMENT PARTICLES ROHM AND HAAS COMPANY (US) 2025-10-16 WO disclosed
US-4008244-A VULCANIZATION ACCELERATORS PENNWALT CORPORATION (US) 1977-02-15 US disclosed
US-3987017-A OXAZOLIDINE- OR THIAZOLIDINE-CARBODI-THIOATES AS CURE ACCELERATORS PENNWALT CORPORATION (US) 1976-10-19 US disclosed
US-3976648-A VULCANIZATION ACCELERATORS PENNWALT CORPORATION (US) 1976-08-24 US disclosed
US-3943143-A Oxazolidine and thiazolidine derived carbodithioate compositions useful as vulcanization accelerators PENNWALT CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087902-A1 Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents PPARG, PPARA, PPARD SLC6A2 3098/4885SLC6A3 1963/4885ADRA1A 49/4885
US-20120270824-A1 MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION MAN2A1, MANBA, M6PR SLC6A2 2156/4885SLC6A3 1541/4885ADRA1A 427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.