SCHEMBL2182248

SCHEMBL2182248

CC(C)C[C@H](NC(=O)[C@@H](N)CS)C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H]([C]=O)CO)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.36
OPRD1 P41143 3/20 0.36
OPRK1 P41145 1/20 0.36
FURIN P09958 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2197175 0.98 FURIN (0.38) OPRM1OPRD1OPRK1FURIN
SCHEMBL2194131 0.90 OPRM1 (0.41) OPRM1OPRD1OPRK1FURIN
SCHEMBL4082464 0.77 OPRM1 (0.39) OPRM1OPRD1OPRK1
SCHEMBL9813485 0.75 MMP2 (0.38) OPRM1OPRD1OPRK1
SCHEMBL29645145 0.75 BACE1 (0.46)
SCHEMBL4086999 0.73 TERT (0.38)
SCHEMBL29822509 0.72 OPRM1 (0.51) OPRM1OPRD1OPRK1
SCHEMBL6240790 0.71 PTGS1 (0.39)
SCHEMBL29576722 0.71 OPRM1 (0.48) OPRM1OPRD1OPRK1
SCHEMBL4082330 0.71 DPP4 (0.35) OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP OPRM1 2317/4885OPRD1 3100/4885OPRK1 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.