Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 8/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919411 | 0.89 | HEXA (0.44) | LCKHEXAHEXBCDK8ACVR1 | |
| Trifluoroacetic Acid SCHEMBL30131250 | 0.78 | ALDH1A1 (0.52) | HEXAHEXBGNRHRBACE1 | |
| SCHEMBL21909057 | 0.77 | HEXA (0.47) | LCKHEXAHEXB | |
| SCHEMBL18942615 | 0.75 | POLB (0.46) | CASP3POLB | |
| SCHEMBL21828451 | 0.75 | GNRHR (0.32) | GNRHRCASP3POLB | |
| Hydrochloric Acid SCHEMBL18919464 | 0.74 | POLB (0.45) | CASP3POLB | |
| SCHEMBL18919421 | 0.74 | GAA (0.41) | CASP3POLB | |
| SCHEMBL18919446 | 0.72 | SMN1; SMN2 (0.47) | CASP3POLB | |
| SCHEMBL21909067 | 0.71 | CDK8 (0.36) | LCKCASP3CDK8ACVR1 | |
| Trifluoroacetic Acid SCHEMBL8142428 | 0.70 | HEXA (0.56) | HEXAHEXB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914240-B | Norbornenone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-3383846-B1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | OTAGO INNOVATION LTD (NZ) | 2022-06-22 | — | — | EP | disclosed |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | OTAGO INNOVATION LIMITED (NZ) | 2021-07-27 | — | — | US | disclosed |
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | LCK 1936/4885HEXA 1682/4885HEXB 1159/4885 |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | HMOX1, MB, NOS2 | LCK 1936/4885HEXA 1682/4885HEXB 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.