Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753531 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CASP3SLC18A3TSHRMEN1 | |
| SCHEMBL10495293 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2TSHRMEN1KMT2AGAA | |
| SCHEMBL18919421 | 0.77 | GAA (0.41) | CASP3TSHRKMT2AGAAPOLB | |
| SCHEMBL18919411 | 0.75 | HEXA (0.44) | TSHRGAA | |
| SCHEMBL10830513 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2CASP3SLC18A3TSHRGAA | |
| SCHEMBL21909067 | 0.73 | CDK8 (0.36) | SMN1; SMN2CASP3TSHRKMT2AGAA | |
| Trifluoroacetic Acid SCHEMBL21828450 | 0.72 | LCK (0.36) | CASP3POLB | |
| SCHEMBL18470154 | 0.72 | ALDH1A1 (0.57) | SMN1; SMN2TSHRMEN1KMT2AGAA | |
| SCHEMBL20574374 | 0.71 | POLB (0.48) | CASP3TSHRMEN1KMT2AGAA | |
| SCHEMBL18942729 | 0.71 | AKT1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383846-B1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | OTAGO INNOVATION LTD (NZ) | 2022-06-22 | — | — | EP | disclosed |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | OTAGO INNOVATION LIMITED (NZ) | 2021-07-27 | — | — | US | disclosed |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | OTAGO INNOVATION LIMITED (NZ) | 2021-07-27 | — | — | US | disclosed |
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-04-09 | — | — | US | disclosed |
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-04-09 | — | — | US | disclosed |
| US-20180346420-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | UNIVERSITY OF OTAGO (NZ) | 2018-12-06 | — | — | US | disclosed |
| EP-3383846-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | Sammut, Ivan Andrew (NZ) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017095237-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | SAMMUT IVAN ANDREW (NZ) | 2017-06-08 | — | — | WO | disclosed |
| WO-2017095237-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | SAMMUT IVAN ANDREW (NZ) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | SMN1; SMN2 947/4885CASP3 71/4885SLC18A3 1115/4885 |
| US-20180346420-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | SMN1; SMN2 947/4885CASP3 71/4885SLC18A3 1115/4885 |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | HMOX1, MB, NOS2 | SMN1; SMN2 947/4885CASP3 71/4885SLC18A3 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.