Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828972 | 0.81 | MAPT (0.61) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL18120560 | 0.77 | MEN1 (0.75) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL17103204 | 0.77 | KMT2A (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL21829030 | 0.76 | NPC1 (0.68) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL21828989 | 0.75 | KMT2A (0.66) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL12845409 | 0.75 | STK39 (0.46) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL21829022 | 0.75 | KMT2A (0.69) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL24004518 | 0.74 | KMT2A (0.64) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL10161848 | 0.74 | KDM4E (0.43) | KMT2ANPC1MEN1ALDH1A1POLB | |
| SCHEMBL21311190 | 0.73 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112888688-A | Benzamide derivatives as CGAS-STING pathway agonists | 巴鲁克斯布伦博格研究所 | 2021-06-01 | — | — | CN | claimed |
| WO-2020072492-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE (US) | 2020-04-09 | — | — | WO | claimed |
| CN-112888688-A | Benzamide derivatives as CGAS-STING pathway agonists | 巴鲁克斯布伦博格研究所 | 2021-06-01 | — | — | CN | disclosed |