Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LIPE | Q05469 | 2/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27888979 | 0.90 | KCNH2 (0.73) | KCNH2HRH3ALDH1A1SMN1; SMN2LIPE | |
| Hydrochloric Acid SCHEMBL27448507 | 0.83 | HRH3 (0.66) | KCNH2HRH3TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2174082 | 0.81 | ADAM10 (0.53) | KCNH2HRH3TSHRBACE1 | |
| SCHEMBL27842786 | 0.80 | RAB9A (0.67) | KCNH2HRH3CYP2C9CYP2C19TSHR | |
| SCHEMBL3666172 | 0.79 | HSD11B1 (0.47) | KCNH2HRH3AKR1C3CYP2C9CYP2C19 | |
| SCHEMBL1531725 | 0.79 | KCNH2 (0.59) | KCNH2HRH3ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3436368 | 0.79 | SMN1; SMN2 (0.60) | AKR1C3CYP2C9CYP2C19TSHRALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27863722 | 0.78 | KCNH2 (0.58) | KCNH2HRH3ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL26986829 | 0.77 | KCNH2 (0.48) | KCNH2HRH3CYP2C19TSHRALDH1A1 | |
| SCHEMBL24937739 | 0.76 | KCNH2 (0.57) | KCNH2HRH3ALDH1A1SMN1; SMN2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680263-B2 | Carbohydrate-based drug delivery polymers and conjugates thereof | NEKTAR THERAPEUTICS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | KCNH2 4789/4885HRH3 4217/4885AKR1C3 935/4885 |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | KCNH2 4644/4885HRH3 2000/4885AKR1C3 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.