SCHEMBL21834239

SCHEMBL21834239

Cc1nnc(CC(O)c2cccc(OCCCC(F)(F)F)c2)o1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 2/20 0.39
▸ CYP2D6 P10635 1/20 0.38
▸ LTB4R Q15722 2/20 0.37
▸ KCNH2 Q12809 2/20 0.37
▸ CACNA1B Q00975 1/20 0.37
▸ ALOX5 P09917 1/20 0.36
▸ MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23243863 0.85 GPR88 (0.46) MAOBCYP2D6KCNH2CACNA1B
SCHEMBL21834303 0.83 MAOB (0.37) MAOBCYP2D6KCNH2CACNA1B
SCHEMBL21834278 0.83 GPR88 (0.35) —
SCHEMBL21834279 0.82 MAOB (0.41) MAOBMAOA
SCHEMBL21834275 0.82 MAOB (0.41) MAOBMAOA
SCHEMBL21834277 0.82 MAOB (0.41) MAOBMAOA
SCHEMBL21834315 0.81 MAOB (0.40) MAOBMAOA
SCHEMBL21834242 0.80 MAOB (0.39) MAOBCYP2D6KCNH2CACNA1BALOX5
SCHEMBL21834297 0.80 MAOB (0.39) MAOBCYP2D6KCNH2CACNA1BALOX5
SCHEMBL21834345 0.76 CYP2D6 (0.39) MAOBCYP2D6KCNH2CACNA1BMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US claimed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US claimed
CN-113272285-B Oxadiazole-containing compound and pharmaceutical composition containing same 爱思开生物制药株式会社 2024-06-07 — — CN claimed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US claimed
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-03-14 — — US claimed
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. 2022-01-27 — — US claimed
CN-113272285-A Oxadiazole-containing compound and pharmaceutical composition containing the same 爱思开生物制药株式会社 2021-08-17 — — CN claimed
EP-3854788-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME SK Biopharmaceuticals Co., Ltd. (KR) 2021-07-28 — — EP claimed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US claimed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US claimed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO claimed
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US disclosed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US disclosed
CN-113272285-B Oxadiazole-containing compound and pharmaceutical composition containing same 爱思开生物制药株式会社 2024-06-07 — — CN disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 MAOB 407/4885CYP2D6 23/4885LTB4R 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback