SCHEMBL21834278

SCHEMBL21834278

Cc1nnc(CC(O)c2cccc(OCC(F)(F)C(F)F)c2)o1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GPR88 Q9GZN0 2/20 0.35
▸ GRIN1 Q05586 4/20 0.33
▸ GRIN2B Q13224 4/20 0.33
▸ HTT P42858 2/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ LMNA P02545 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ AOC3 Q16853 2/20 0.32
▸ CTSA P10619 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23243849 0.86 GPR88 (0.47) GPR88HTTSMN1; SMN2KMT2ACTSA
SCHEMBL21834255 0.83 GPR88 (0.36) GPR88GRIN1GRIN2BHTTSMN1; SMN2
SCHEMBL21834239 0.83 MAOB (0.39) —
SCHEMBL29229802 0.78 L3MBTL1 (0.35) GPR88HTTAOC3CTSA
SCHEMBL21834336 0.77 GRIN1 (0.33) GRIN1GRIN2BHTTSMN1; SMN2MAPK1
SCHEMBL29229794 0.77 GPR88 (0.37) GPR88HTTAOC3CTSA
SCHEMBL21834310 0.74 CTSA (0.47) CTSA
SCHEMBL21834256 0.73 CTSA (0.43) GRIN1GRIN2BSMN1; SMN2HPGDNPSR1
SCHEMBL21834273 0.73 CTSA (0.43) GRIN1GRIN2BSMN1; SMN2HPGDNPSR1
SCHEMBL21834254 0.73 CTSA (0.43) GRIN1GRIN2BSMN1; SMN2HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US claimed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US claimed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US claimed
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-03-14 — — US claimed
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. 2022-01-27 — — US claimed
CN-113272285-A Oxadiazole-containing compound and pharmaceutical composition containing the same 爱思开生物制药株式会社 2021-08-17 — — CN claimed
EP-3854788-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME SK Biopharmaceuticals Co., Ltd. (KR) 2021-07-28 — — EP claimed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US claimed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US claimed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO claimed
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US disclosed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 GPR88 2939/4885GRIN1 95/4885GRIN2B 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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