Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21812922 | 0.88 | UCHL1 (0.44) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834637 | 0.86 | NPC1 (0.51) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834551 | 0.85 | GRM1 (0.57) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21812661 | 0.82 | MAPT (0.48) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834575 | 0.81 | RAB9A (0.46) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834573 | 0.81 | NPC1 (0.56) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834645 | 0.80 | NPC1 (0.54) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834566 | 0.79 | RAB9A (0.47) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834549 | 0.78 | GRM1 (0.52) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21834679 | 0.78 | RAB9A (0.43) | MAPTRAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |