Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834629 | 0.89 | UCHL1 (0.41) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834645 | 0.85 | NPC1 (0.54) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834623 | 0.85 | UCHL1 (0.49) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21812701 | 0.82 | HTR6 (0.40) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834678 | 0.81 | PTPN1 (0.42) | SMN1; SMN2RAB9ALMNAMAPTKMT2A | |
| SCHEMBL21834630 | 0.81 | DRD3 (0.41) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834574 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834607 | 0.79 | MAPT (0.45) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834679 | 0.79 | RAB9A (0.43) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL21834561 | 0.78 | NPC1 (0.49) | SMN1; SMN2RAB9ALMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |